Nervisign-300 (Pregabalin Capsules IP 300mg)

Nervisign-300 (Pregabalin Capsules IP 300mg)

Advanced Neuropathic Pain Relief and Nerve Health Support

Overview

Nervisign-300 (Pregabalin Capsules IP 300mg) is a prescription medication formulated to provide effective relief from neuropathic pain, fibromyalgia, generalized anxiety disorder (GAD), and certain types of seizures. Manufactured by HAB Pharmaceuticals & Research Limited, this pharmaceutical-grade preparation contains Pregabalin 300mg as its active ingredient, designed to modulate overactive nerve signals in the brain and spinal cord.

Nervisign-300 is clinically recognized for its role in reducing nerve pain intensity, improving sleep patterns, and stabilizing neurological functions. It is prescribed globally by healthcare professionals for patients suffering from diabetic neuropathy, post-herpetic neuralgia, spinal cord injury-related pain, and partial-onset seizures.

Composition

• Active Ingredient: Pregabalin IP 300mg
• Formulation: Hard gelatin capsules
• Colour: Approved red and white color combination
• Excipients: Pharmaceutical-grade inactive ingredients for stability and absorption
• Packaging: 10×15 blister pack (150 capsules)
• Manufacturer: HAB Pharmaceuticals & Research Limited, India

Pharmacological Class

• Drug Class: Anticonvulsant / Neuropathic pain agent
• Mechanism of Action: Alpha-2-delta (α2δ) subunit ligand of voltage-gated calcium channels

Mechanism of Action – How Nervisign-300 Works

Pregabalin, the active component of Nervisign-300, works by binding to the alpha-2-delta subunit of voltage-gated calcium channels in the central nervous system. This action reduces the release of several neurotransmitters such as glutamate, norepinephrine, and substance P, which are responsible for transmitting pain signals.

By modulating abnormal nerve activity, Pregabalin helps calm overactive neurons, preventing excessive electrical discharges that cause pain, anxiety, and seizures. As a result, Nervisign-300 restores nerve balance, relieves chronic discomfort, and improves neurological stability.

Therapeutic Uses

Nervisign-300 is indicated for the management of multiple neurological and psychiatric conditions:

1. Neuropathic Pain:
   • Diabetic Peripheral Neuropathy: Reduces burning, tingling, and shooting pain caused by nerve damage in diabetes.
   • Post-Herpetic Neuralgia: Alleviates long-term pain following shingles infection.
   • Spinal Cord Injury Pain: Provides relief from nerve-related pain after spinal trauma.
2. Fibromyalgia:
   • Helps relieve widespread muscle pain, stiffness, and tenderness associated with fibromyalgia syndrome.
   • Improves sleep quality and physical functionality in affected individuals.
3. Generalized Anxiety Disorder (GAD):
   • Reduces symptoms such as excessive worry, restlessness, and nervous tension by stabilizing neurotransmitter activity.
4. Seizure Disorders (Adjunctive Therapy):
   • Used as an additional medication for partial-onset seizures to control epileptic episodes effectively.

Key Features

• High Potency: Each capsule contains 300mg of pure Pregabalin for maximum therapeutic effect.
• Clinically Tested: Proven efficacy in managing nerve pain and anxiety-related disorders.
• Fast-Acting Formula: Rapid absorption ensures prompt relief from nerve discomfort.
• Convenient Oral Capsule: Easy-to-swallow hard gelatin form for daily use.
• Pharmaceutical-Grade Manufacturing: Produced under stringent quality and GMP standards.
• Stable Shelf Life: Formulated for optimal stability and potency during storage.
• Professional Packaging: Blister-sealed for hygiene and protection from moisture.

Benefits of Nervisign-300

1. Effective Pain Management
   Nervisign-300 provides consistent relief from chronic neuropathic pain, making it easier for patients to carry out daily activities without discomfort.
2. Enhanced Sleep and Mood
   By reducing nerve sensitivity and calming neural activity, it improves sleep cycles and reduces restlessness associated with pain or anxiety.
3. Improved Cognitive Function
   Patients often report better concentration and reduced fatigue as nerve overactivity is regulated.
4. Reduction in Seizure Frequency
   As an adjunct therapy, Pregabalin helps lower seizure frequency in individuals with partial epilepsy.
5. Support for Emotional Stability
   Pregabalin’s effect on neurotransmitters such as GABA contributes to emotional balance and relief from anxiety.
6. Improved Quality of Life
   Regular use as prescribed by a physician enhances overall well-being, comfort, and daily productivity.

Target Audience

• Adults diagnosed with diabetic neuropathy or nerve-related pain.
• Patients suffering from fibromyalgia or chronic musculoskeletal discomfort.
• Individuals under treatment for generalized anxiety disorder (GAD).
• Patients requiring adjunctive therapy for seizures.
• People with post-herpetic neuralgia (pain after shingles).

Dosage and Administration

• Usual Adult Dose: As prescribed by a physician.
  • Typically initiated with a lower dose (e.g., 75mg or 150mg) and titrated up to 300mg per day depending on patient tolerance and medical condition.
• Administration: Oral, with or without food.
• Frequency: Once or twice daily as per medical direction.
• Important: Do not crush or chew capsules; swallow whole with water.

Always follow the physician’s dosage instructions precisely. Do not self-medicate or alter the prescribed schedule.

Storage Information

• Store at a temperature below 30°C.
• Keep away from moisture, heat, and direct sunlight.
• Keep out of reach of children.

Precautions and Safety Information

• Medical Supervision Required: Nervisign-300 is a prescription-only medicine and should be used strictly under medical advice.
• Pregnancy & Lactation: Should be used only if clearly prescribed by a doctor.
• Alcohol: Avoid alcohol consumption while on Pregabalin therapy, as it may enhance dizziness or drowsiness.
• Driving & Machinery: Pregabalin can cause dizziness and sleepiness; refrain from driving or operating heavy machinery until you know its effects.
• Renal Impairment: Dose adjustment may be required for patients with kidney disorders.
• Drug Interactions: Inform your healthcare provider about all medications, supplements, or herbal products you are taking.

Possible Side Effects

While generally well tolerated, some individuals may experience mild to moderate side effects, including:

• Drowsiness or fatigue
• Dizziness or unsteadiness
• Weight gain
• Blurred vision
• Dry mouth
• Swelling of hands or feet (edema)

If side effects persist or worsen, consult your healthcare provider immediately.

Why Choose Nervisign-300?

1. Trusted Manufacturer: Produced by HAB Pharmaceuticals & Research Limited, known for quality pharmaceutical formulations.
2. Clinically Validated: Backed by scientific research and therapeutic efficacy.
3. Consistent Pain Relief: Designed to maintain stable plasma levels for long-lasting relief.
4. Broad Therapeutic Use: Effective across pain, anxiety, and seizure conditions.
5. Improved Patient Compliance: Once or twice-daily dosage enhances adherence.

How Pregabalin Differs from Other Pain Relievers

Unlike traditional painkillers or anti-inflammatory drugs that act on peripheral pain pathways, Pregabalin acts centrally — directly influencing the nerve cells responsible for pain transmission. This makes Nervisign-300 particularly beneficial for neuropathic pain, where conventional painkillers often fail.

It not only relieves pain but also addresses the underlying neural dysfunction, making it a superior choice for chronic nerve-related conditions.

Clinical Evidence and Efficacy

Extensive clinical trials have demonstrated Pregabalin’s effectiveness in reducing pain scores and improving overall quality of life. Studies confirm significant relief within the first few weeks of therapy in patients with diabetic neuropathy and fibromyalgia. Moreover, consistent use has shown marked improvements in anxiety reduction and seizure control when used as adjunctive therapy.

Patient Guidance

• Take the medication at the same time each day for best results.
• Do not abruptly discontinue without consulting your doctor, as this may cause withdrawal symptoms.
• Inform your physician if you experience mood changes, depression, or suicidal thoughts.
• Maintain a healthy lifestyle, including proper sleep and a balanced diet, to enhance treatment effectiveness.

Professional Insight

For healthcare professionals, Nervisign-300 (Pregabalin 300mg) serves as a reliable therapeutic option due to its predictable pharmacokinetics, high bioavailability, and low potential for drug interactions. Its role in both neuropathic pain and psychiatric stabilization makes it a versatile agent in clinical practice.

It is especially beneficial for patients with mixed pain syndromes—conditions where neuropathic and musculoskeletal components overlap, such as in fibromyalgia or chronic back pain.

Conclusion

Nervisign-300 (Pregabalin Capsules IP 300mg) is a scientifically developed and clinically validated medication that delivers powerful, targeted relief from neuropathic pain, fibromyalgia, seizures, and anxiety disorders. By stabilizing nerve cell activity, it effectively restores comfort, improves sleep, and enhances the overall quality of life.

Backed by HAB Pharmaceuticals’ trusted manufacturing standards, Nervisign-300 stands as a professional-grade solution for physicians and patients seeking reliable and sustained nerve pain management.

For individuals living with chronic nerve pain or anxiety, Nervisign-300 offers a path to comfort, control, and confidence under proper medical guidance.

Disclaimer:
This content is for informational and educational purposes only. Nervisign-300 (Pregabalin Capsules IP 300mg) is a prescription medication that should be used only under the supervision of a licensed healthcare professional. Always follow your physician’s advice regarding dosage, duration, and safety precautions.